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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY1
All Species:
31.82
Human Site:
S280
Identified Species:
53.85
UniProt:
Q16526
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16526
NP_004066.1
586
66395
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Chimpanzee
Pan troglodytes
XP_509339
586
66344
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Rhesus Macaque
Macaca mulatta
XP_001100653
586
66450
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Dog
Lupus familis
XP_531757
606
68237
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
P97784
606
67983
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Rat
Rattus norvegicus
Q32Q86
588
66212
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508613
577
65001
S241
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Chicken
Gallus gallus
Q8QG61
621
69654
S280
Y
K
K
V
K
K
N
S
S
P
P
L
S
L
Y
Frog
Xenopus laevis
Q75WS4
523
60626
N245
A
S
Y
K
D
T
R
N
G
L
I
G
L
D
Y
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
R243
V
A
T
Y
K
E
T
R
N
G
M
I
G
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
E246
K
V
E
Q
H
A
F
E
R
G
F
Y
L
P
N
Honey Bee
Apis mellifera
NP_001077099
570
65246
A297
L
Y
K
K
I
K
K
A
V
P
P
L
S
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
L240
K
Q
R
L
D
R
H
L
E
R
K
A
W
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
K276
Q
I
I
W
A
R
D
K
N
S
E
G
E
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
95.3
N.A.
93.5
96.2
N.A.
85.3
87.5
25.7
25
N.A.
37.2
65.3
N.A.
59.5
Protein Similarity:
100
100
99.6
95.8
N.A.
94.7
97.7
N.A.
89.2
92.1
43.5
42.3
N.A.
53.7
78.5
N.A.
70.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
6.6
N.A.
0
46.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
13.3
33.3
N.A.
6.6
60
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
8
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
8
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
8
0
0
8
0
8
8
0
8
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
15
0
15
8
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
8
0
8
0
0
0
0
0
8
8
0
0
0
% I
% Lys:
15
58
65
15
65
65
8
8
0
0
8
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
8
0
8
0
65
15
65
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
58
8
15
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
65
65
0
0
8
0
% P
% Gln:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
15
8
8
8
8
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
58
58
8
0
0
65
0
8
% S
% Thr:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
58
0
0
0
0
8
0
0
0
0
15
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
58
8
8
8
0
0
0
0
0
0
0
8
0
0
65
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _